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Physiological Integrity – Physiological Adaptation
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Question 1 of 50
1. A client has a postoperative wound infection. Which assessment finding should the practical nurse report to the RN immediately?
Question 2 of 50
2. A client is being treated for sepsis. The practical nurse understands that which intervention is the HIGHEST priority during the first hour of sepsis recognition?
Question 3 of 50
3. A client with a urinary tract infection develops the following vital signs: temperature 101.8°F (38.8°C), heart rate 118 bpm, respiratory rate 24/min, WBC 16,000/mm³. The practical nurse recognizes these findings meet the criteria for:
Question 4 of 50
4. A 72-year-old client with a central venous catheter develops fever, chills, and confusion. Blood cultures are positive for Staphylococcus aureus. The practical nurse suspects central line-associated bloodstream infection (CLABSI). Which action is most appropriate for the PN to take?
Question 5 of 50
5. Which assessment finding is the EARLIEST indicator that a client with sepsis is progressing to septic shock?
Question 6 of 50
6. A client with pneumonia is receiving IV antibiotics. The practical nurse knows that which action is most important for preventing the development of sepsis?
Question 7 of 50
7. A client with a stage 3 pressure injury on the sacrum has the following assessment findings: temperature 102.2°F (39°C), heart rate 110 bpm, wound with foul-smelling purulent drainage, and surrounding erythema. Which intervention should the practical nurse implement FIRST?
Question 8 of 50
8. A client who underwent abdominal surgery 3 days ago has the following findings: temperature 99.8°F (37.7°C), incision with slight serous drainage, WBC 11,500/mm³, and states “I feel fine.” On day 4, the temperature is 101.6°F (38.7°C), WBC is 18,000/mm³, incision has purulent drainage with increased redness, and the client reports feeling “weak and dizzy.” The practical nurse interprets these findings as:
Question 9 of 50
9. A client with a Foley catheter has been diagnosed with a catheter-associated urinary tract infection (CAUTI). Which action by the practical nurse is most important for preventing future CAUTIs?
Question 10 of 50
10. The practical nurse is caring for a client on contact precautions for methicillin-resistant Staphylococcus aureus (MRSA). Which personal protective equipment (PPE) is required when entering the client’s room?
Question 11 of 50
11. A client with type 1 diabetes is found confused and diaphoretic. A fingerstick blood glucose reads 42 mg/dL. The client is awake but unable to swallow safely. Which action should the LPN/LVN take FIRST?
Question 12 of 50
12. A client is admitted with diabetic ketoacidosis. The LPN/LVN expects to observe which classic respiratory pattern associated with this metabolic emergency?
Question 13 of 50
13. An elderly client with type 2 diabetes is brought to the emergency department with extreme dehydration, confusion, and a blood glucose of 650 mg/dL. There is no fruity breath odor, and urine ketones are negative. The LPN/LVN recognizes these findings as most consistent with:
Question 14 of 50
14. A client with Graves’ disease develops a fever of 103°F (39.4°C), heart rate of 140 bpm, and severe agitation. The LPN/LVN suspects thyroid storm and should anticipate administering which medication FIRST?
Question 15 of 50
15. A client with a history of hypothyroidism is found unconscious with a body temperature of 93°F (33.9°C), bradycardia (HR 48 bpm), and hypotension. The LPN/LVN recognizes this as myxedema coma and understands that which intervention is the priority?
Question 16 of 50
16. A client with Addison’s disease presents with severe hypotension (BP 78/40), abdominal pain, vomiting, and hypoglycemia after missing several doses of hydrocortisone. The LPN/LVN should anticipate which immediate intervention?
Question 17 of 50
17. According to standard hypoglycemia treatment protocols, after administering 15 grams of fast-acting carbohydrate to a conscious client with blood glucose of 55 mg/dL, when should the LPN/LVN recheck the blood glucose?
Question 18 of 50
18. A client is being treated for diabetic ketoacidosis with IV insulin and fluids. Which laboratory value requires the MOST vigilant monitoring during the first 24 hours of treatment?
Question 19 of 50
19. A client with hyperparathyroidism has a serum calcium level of 14.2 mg/dL (normal: 8.6-10.2 mg/dL). The LPN/LVN should monitor this client MOST closely for which complication?
Question 20 of 50
20. The LPN/LVN is teaching a client with type 1 diabetes about preventing hypoglycemic emergencies. Which statement by the client indicates a need for further teaching?
Question 21 of 50
21. A client arrives at the emergency department with sudden onset of facial drooping, arm weakness, and slurred speech that began 2 hours ago. The spouse reports the symptoms started while watching television. Which action should the PN prioritize FIRST?
Question 22 of 50
22. A client with a diagnosed ischemic stroke is being evaluated for thrombolytic therapy (tPA). The PN reviews the client’s history. Which finding is a CONTRAINDICATION for tPA administration?
Question 23 of 50
23. A client with traumatic brain injury has an intracranial pressure (ICP) monitoring device in place. The PN notes the ICP reading is 22 mmHg. Which action should the PN take FIRST?
Question 24 of 50
24. The PN is caring for a client with increased intracranial pressure. Which assessment finding indicates the EARLIEST sign of neurological deterioration?
Question 25 of 50
25. A client with a spinal cord injury at T4 reports a severe pounding headache and is sweating profusely above the level of injury. The blood pressure is 210/110 mmHg. Which action should the PN take FIRST?
Question 26 of 50
26. A client is having a generalized tonic-clonic seizure in the hospital room. Which action by the PN is MOST appropriate during the seizure?
Question 27 of 50
27. A client who just experienced a seizure is in the postictal state. Which assessment is the PN’s priority during this phase?
Question 28 of 50
28. A client with a suspected stroke is being assessed using the FAST acronym. Which finding corresponds to the “S” in FAST?
Question 29 of 50
29. A client with increased ICP is receiving mannitol (Osmitrol) IV. Which assessment finding indicates the medication is effective?
Question 30 of 50
30. A client with a spinal cord injury at T3 is being educated about preventing autonomic dysreflexia. Which instruction should the PN include in the teaching plan? (Select all that apply.)
Question 31 of 50
31. ### Question
The nurse is caring for a client in hypovolemic shock. Which of the following assessment findings should the nurse expect?
Question 32 of 50
32. ### Question
A client presents with a severe allergic reaction after receiving IV penicillin. The client is experiencing stridor, wheezing, and facial swelling. The nurse should recognize that the client is most likely experiencing which type of shock?
Question 33 of 50
33. ### Question
The nurse is assisting with the care of a client in septic shock who is receiving a norepinephrine infusion. Which finding indicates the vasopressor therapy is effective?
Question 34 of 50
34. ### Question
The nurse is performing a primary survey on a trauma client using the ABCDE approach. Which assessment should the nurse perform first?
Question 35 of 50
35. ### Question
A 68-year-old client presents to the emergency department with chest pain, shortness of breath, and diaphoresis. Assessment reveals blood pressure 84/50 mm Hg, heart rate 120 beats/minute, respiratory rate 28 breaths/minute, and jugular venous distension. Heart sounds reveal an S3 gallop. The nurse should recognize that this client is most likely experiencing which type of shock?
Question 36 of 50
36. ### Question
The nurse is caring for a client who sustained multiple injuries in a motor vehicle collision. The client has an open chest wound, a fractured femur, and facial lacerations. Using the ABCDE framework, which injury should the nurse address first?
Question 37 of 50
37. ### Question
A client with a spinal cord injury at the T4 level is brought to the emergency department. The nurse notes hypotension, bradycardia, and warm, dry skin. The nurse should recognize these findings as characteristic of which type of shock?
Question 38 of 50
38. ### Question
The nurse is caring for a client who received a blood transfusion 15 minutes ago. The client now reports difficulty breathing and appears anxious. Assessment reveals a blood pressure of 88/54 mm Hg, heart rate 118 beats/minute, respiratory rate 32 breaths/minute, and urticaria on the chest. Which action should the nurse take first?
Question 39 of 50
39. ### Question
The nurse is reviewing laboratory results for a client in septic shock. Which finding should the nurse report to the healthcare provider immediately?
Question 40 of 50
40. ### Question
A client arrives at the emergency department with a penetrating chest wound from a stabbing. The nurse notes a small open wound on the left chest with a sucking sound on inspiration. The client’s oxygen saturation is 88% on room air. Which intervention should the nurse implement first?
Question 41 of 50
41. A client with a history of hypertension arrives at the emergency department complaining of severe chest pain radiating to the left arm. The client is diaphoretic and appears anxious. Vital signs: BP 188/102, HR 118, RR 28, SpO2 91% on room air. What is the LPN/LVN’s priority action?
Question 42 of 50
42. The LPN/LVN is caring for a client diagnosed with a pulmonary embolism. Which assessment finding would indicate the greatest concern for deterioration?
Question 43 of 50
43. A client with diabetic ketoacidosis (DKA) has been receiving IV insulin and fluid resuscitation for 6 hours. Current laboratory values show: glucose 180 mg/dL, potassium 3.1 mEq/L, sodium 138 mEq/L, pH 7.32. The client’s IV fluid is D5W with 0.45% normal saline running at 100 mL/hr. What action should the LPN/LVN anticipate?
Question 44 of 50
44. A client receiving a heparin infusion for deep vein thrombosis has an aPTT of 98 seconds (control: 30 seconds). The heparin protocol states: aPTT 81-100 seconds = decrease infusion rate by 2 units/kg/hr. Current infusion rate is 18 units/kg/hr. The client has no signs of bleeding. What is the LPN/LVN’s appropriate action?
Question 45 of 50
45. A client with a urinary tract infection has developed sepsis. Current vital signs: temperature 39.4°C (102.9°F), heart rate 126, blood pressure 88/52, respiratory rate 24, SpO2 94% on 2L oxygen. The provider has ordered IV antibiotics, blood cultures, and a 500 mL normal saline bolus. Which intervention should the LPN/LVN perform FIRST?
Question 46 of 50
46. A client is admitted with a diagnosis of hyperosmolar hyperglycemic state (HHS). Which laboratory finding would the LPN/LVN expect to see?
Question 47 of 50
47. A client sustained a traumatic brain injury 24 hours ago. The LPN/LVN notes the following changes from the previous assessment: Glasgow Coma Scale decreased from 13 to 9, right pupil is 5mm and nonreactive (left is 3mm and reactive), and the client is exhibiting decorticate posturing. What is the priority interpretation of these findings?
Question 48 of 50
48. A client arrives at the emergency department after a motor vehicle accident with multiple injuries. The client is pale, cool, and clammy with a heart rate of 134, blood pressure of 82/50, and barely palpable peripheral pulses. The LPN/LVN recognizes these findings as indicative of which type of shock?
Question 49 of 50
49. A client with acute heart failure is receiving IV furosemide (Lasix) 40 mg. The LPN/LVN should monitor for which expected therapeutic effect?
Question 50 of 50
50. The LPN/LVN is caring for a client with chronic obstructive pulmonary disease (COPD) who is experiencing an acute exacerbation. Which oxygen delivery method is most appropriate for this client?
Ready to sharpen your clinical judgment? This free NCLEX-PN Physiological Integrity: Physiological Adaptation Practice Test – Part 2 (Updated 2026) gives you 50 exam-style questions that mirror the NCLEX-PN format, covering the acute and chronic condition management you’ll see on test day. Work through each item carefully and treat this as a realistic rehearsal for the real thing.
Pro Tips for Success
Manage your time: Aim for about one minute per question so you build the pacing you’ll need on the actual NCLEX-PN, and flag lengthy items to revisit rather than getting stuck.
Review your weak areas: After finishing, note every topic you missed and spend extra study time on those physiological adaptation concepts before retaking the test.
This test covers:
– Physiological Integrity – Physiological Adaptation (50 questions) – managing acute and chronic illness and medical emergencies
? More NCLEX-PN Practice Tests: